LEBER HEREDITARY OPTIC NEUROPATHY: DO FOLATE PATHWAY GENE ALTERATIONS INFLUENCE THE EXPRESSION OF MITOCHONDRIAL DNA MUTATION?

Leber Hereditary Optic Neuropathy: Do Folate Pathway Gene Alterations Influence the Expression of Mitochondrial DNA Mutation?

"nBackground: Leber hereditary optic neuropathy (LHON) is an inherited form of bilateral optic atrophy leading to the loss of central vision.  The primary cause of vision loss is mutation in the mitochondrial DNA (mtDNA), however, unknown secon­dary genetic and/or epigenetic risk factors are suggested to influence its neuropat

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A Web-Based Patient Empowerment to Medication Adherence Program for Patients With Rheumatoid Arthritis: Feasibility Randomized Controlled Trial

BackgroundLiving with a chronic illness such as rheumatoid arthritis (RA) requires medications and therapies, as well as long-term follow-up with multidisciplinary clinical teams.Patient involvement in the shared decision-making process on medication regimens is an important element in promoting medication adherence.Literature review and needs asse

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Diagnostic Accuracy of Delayed Phase Post Contrast Computed Tomographic Images in the Diagnosis of Focal Liver Lesions in Dogs: 69 Cases

To describe the computed tomographic (CT) features of focal liver lesions (FLLs) in dogs, that could enable predicting lesion histotype.Dogs diagnosed with FLLs through both CT and cytopathology and/or histopathology were retrospectively lindell lin76 collected.Ten qualitative and 6 quantitative CT features have been described for each case.Lastly,

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